基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體
Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3)
SL1; STMY; STMY1; STR1; Progelatinase; Stromelysin 1; Transin-1
- 編號UMAA101Ra21
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)A3
- Ig亞型 IgG2b Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPA101Ra01-基質(zhì)金屬蛋白酶3(MMP3)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用IHC
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 326 ¥ 760 ¥ 1086 ¥ 2715 ¥ 10860
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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DAB staining on IHC-P; Samples: Rat Kidney Tissue; Primary Ab: 30μg/ml Mouse Anti-Rat MMP3 Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
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DAB staining on IHC-P;
Samples: Rat Liver Tissue;
Primary Ab: 30μg/ml Mouse Anti-Rat MMP3 Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
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Figure. Western Blot; Sample: Recombinant MMP3, Rat.
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對MMP3的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別MMP3。
用法
Western blotting: 0.01-3μg/mL;
Immunohistochemistry: 5-30μg/mL;
Immunocytochemistry: 5-30μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA101Ra01 | 基質(zhì)金屬蛋白酶3(MMP3)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA101Ra02 | 基質(zhì)金屬蛋白酶3(MMP3)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA101Ra03 | 基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAA101Ra04 | 基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體 | WB; IHC; ICC; IP. |
| UPAA101Ra01 | 基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體 | IHC |
| UPAA101Ra02 | 基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體 | IHC; ICC/IF |
| ULAA101Ra71 | 基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| ULAA101Ra81 | 基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體(異硫氰酸熒光素標記) | WB; IHC; ICC; IF. |
| UMAA101Ra22 | 基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體 | WB |
| UMAA101Ra21 | 基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體 | IHC |
| UMAA101Ra23 | 基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體 | WB; IHC; ICC; IP. |
| USEA101Ra | 基質(zhì)金屬蛋白酶3(MMP3)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCA101Ra | 基質(zhì)金屬蛋白酶3(MMP3)檢測試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA101Ra | 基質(zhì)金屬蛋白酶3(MMP3)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
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| Biol Res | The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis [PubMed: 26578310] |
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| Molecular Medicine Reports | Icariin inhibits MMP?1, MMP?3 and MMP?13 expression through MAPK pathways in IL?1β?stimulated SW1353 chondrosarcoma cells [pubmed:28447732] |
| der Christian-Albrechts-Universit?t zu Kiel | Wirkung schonender Laserverfahren auf den Komplexaus retinalem Pigmentepithel, Bruch′scher Membranund Choroidea - m?gliche Therapieoption der frühen altersabh?ngigen Makuladegeneration [1133074014:34] |
| REDVET - Revista electrónica de Veterinaria | Measurement of Metalloproteinase-3 levels in synovial fluid from horses as biomarker of joint disease [E-ISSN: 1695-7504] |
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| Molecular Pharmacology | Dexamethasone Down-regulates Endothelin Receptors and Reduces Endothelin-induced Production of Matrix Metalloproteinases in Cultured Rat Astrocytes [10.1124/mol.116.107300] |
| Theranostics | Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis [Pubmed:29774078] |
| Chinese Journal of Integrative Medicine | Electroacupuncture Delays Cartilage Degeneration by Modulating Nuclear Factor-κB Signaling Pathway [Pubmed: 30656598] |
| Effects of a hyperimmunized egg product on voluntary physical activity levels, serum inflammatory markers, and owner perception of joint pain of dogs with?… [] | |
| PLoS One | Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis [Pubmed: 30939166] |
| ACS Biomaterials Science & Engineering | Fluorogenic Probe for Detecting Active Matrix Metalloproteinase-3 (MMP-3) in Plasma and Peripheral Blood Neutrophils to Indicate the Severity of Rheumatoid?… [] |
| World Journal of Pediatrics | Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis [Pubmed: 31641939] |
| International Journal of Molecular Sciences | Matrix Metalloproteinase-3 is Key Effector of TNF-α-Induced Collagen Degradation in Skin [Pubmed: 31652545] |
| JOURNAL OF CELLULAR BIOCHEMISTRY | Teneligliptin inhibits IL‐1β‐induced degradation of extracellular matrix in human chondrocytes [Pubmed: 32162384] |
| Bone Research | Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritis [Pubmed: 32047705] |
| Scientific Reports | Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis [Pubmed: 31980722] |
| Alexandria Journal for Veterinary Sciences | The Clinicopathological Picture of Some Postpartum Disorders in Barki Ewes. [] |
| Identification of Polyphenolic Compounds and Hepatoprotective Activity of Artichoke (Cynara Scolymus L.) Edible Part Extracts in Rats [] | |
| Food Funct | Undenatured type II collagen prevents and treats the osteoarthritis and motor function degradation in T2DM patients and db/db mice [33890588] |
| journal biomedicine translational research | Peanut (Arachis hypogaea) Shells Extract and Apis dorsata Honey Reduce Matrix Metalloproteinase-3 in Monosodium Iodoacetate-Induced Osteoarthritic??- [] |
| JOURNAL OF ANIMAL SCIENCE | Physical Activity Patterns of Free Living Dogs Diagnosed with Osteoarthritis [34216471] |
| Osteoarthritis Cartilage | A systematic review on the potential value of synovial fluid biomarkers to predict clinical outcomes in cartilage repair treatments [Pubmed:35618204] |
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| Journal of Immunology Research | Ebosin Attenuates the Inflammatory Responses Induced by TNF-α through Inhibiting NF-κB and MAPK Pathways in Rat Fibroblast-Like Synoviocytes [Pubmed:35340587] |
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