腎酶(RNLS)重組蛋白
Recombinant Renalase (RNLS)
MAO-C; C10orf59; FAD-Dependent Amine Oxidase; Monoamine oxidase-C; alpha-NAD(P)H oxidase/anomerase
- 編號(hào)URPC845Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱(chēng)，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌
- 預(yù)測(cè)分子量18.5kDa
- 實(shí)際分子量19kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Ala18~Ser150 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)6.9
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 550 ¥ 1374 ¥ 2748 ¥ 8244 ¥ 20610
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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SDS-PAGE圖
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPC845Ra01 | 腎酶(RNLS)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAC845Ra01 | 腎酶(RNLS)多克隆抗體 | WB; IHC; ICC; IP. |
| UMAC845Ra21 | 腎酶(RNLS)單克隆抗體 | WB; IHC; ICC; IP. |
| USEC845Ra | 腎酶(RNLS)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMC845Ra | 腎酶(RNLS)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Pol Arch Med Wewn. | Renalase, kidney function, and markers of endothelial dysfunction in renal transplant recipients [Cartelcolor: source] |
| Angiology | Renalase, Stroke, and Hypertension in Hemodialyzed Patients [PubMed: 22583169] |
| Peritoneal dialysis international | Renalase in peritoneal dialysis patients is not related to blood pressure, but to dialysis vintage. [Pdiconnect: Source] |
| Archives of Medical Science | Vascular adhesion protein-1 and renalase in regard to diabetes in hemodialysis patients [PubMed: PMC3542495] |
| Renal Failure | Circulating Levels of Renalase, Norepinephrine, and Dopamine in Dialysis Patients [Pubmed: 23530612] |
| Borgis - Postepy Nauk Medycznych | VAP-1 in chronic kidney disease and diabetic kidney disease [Czytelniamedyczna: Source] |
| Journal of Basic and Clinical Physiology and Pharmacology | The relationship between dopamine and renalase in type 2 diabetic patients with and without diabetic nephropathy [Pubmed: 15365253] |
| Exp Biol Med (Maywood). | Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients. [Pubmed: 24599883] |
| Kidney Blood Press Res. | Renalase, a novel enzyme involved in blood pressure regulation, is related to kidney function but not to blood pressure in hemodialysis patients. [Pubmed: 22539018] |
| Nephrology Dialysis Transplantation | Renalase in hypertension and kidney disease [Oxfordjournals: Source] |
| Lipids in Health and Disease | Markers of increased cardiovascular risk in patients with chronic kidney disease [Biomedcentral:Source] |
| Research & Experimental? | Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients [Pubmed:24599883] |
| Pediatr Nephrol | Normal values for urine renalase excretion in children [Pubmed:25060760] |
| J Am Soc Hypertens. | Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta [Pubmed:25064768] |
| Cardiology. | Effect of salt intake and potassium supplementation on urinary renalase and serum dopamine levels in Chinese adults [Pubmed:25824645] |
| J Am Soc Hypertens | Circulating renalase, catecholamines, and vascular adhesion [PubMed: 26403854] |
| Indian Pediatr | Renalase levels in children with solitary functioning kidney [PubMed: 26713989] |
| Oxford Journals | SP321 RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS [Content: 30] |
| journal of hypertension | PP.27.07: PREHYPERTENSIVE ALTERATIONS OF ARTERIAL AND VENOUS REACTIVITY IN A RAT POLYCYSTIC OVARY SYNDROME MODEL. EFFECTS OF PARALLEL VITAMIN D3 ADMINISTRATION [Jhypertension: Abstract] |
| journal of hypertension | PP.27.06: RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS. [Jhypertension: Abstract] |
| journal of hypertension | PP.27.04: ENDOTHELIAL DYSFUNCTION AND ARTERIAL HYPERTENSION IN THE WORKING POPULATION (MERIDIAN STUDY). [Jhypertension: Abstract] |
| Curr Vasc Pharmacol. | Renalase is Removed by Kidneys and During Dialysis – Excess Related to CKD Complications? [PubMed: 25515790] |
| Kidney Blood Press Res | Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt Diet [PubMed: 26619289] |
| PLoS One | Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis [PubMed: 26431044] |
| J Hum Hypertens | Plasma renalase concentration before and after radiofrequency renal denervation in patients with resistant hypertension [PubMed: 26310184] |
| Nephrology (Carlton) | Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography. [pubmed:27778420] |
| Nephrol Dial Transplant | PLASMA RENALASE CONCENTRATION BEFORE AND AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION: PRELIMINARY RESULTS [content:31] |
| Renal?Failure | Increased?serum?renalase?in?hemodialysis?patients: is it?related?to?left ventricular hypertrophy? [pubmed:27416751] |
| Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants | High-performance Liquid Chromatography?Measured?Metabolites?of?EndogenousCatecholamines and Their Relations to Chronic Kidney Disease and?High?Blood?Pressure?in Heart Transplant Recipients. [pubmed:27496485] |
| PLOS?ONE | Online Haemodiafiltration Improves Inflammatory State in Dialysis Patients: A Longitudinal Study. [pubmed:27783636] |
| Advances in Experimental Medicine and Biology | Renalase in Children with Glomerular Kidney Diseases [chapter:10.1007] |
| Kidney & Blood Pressure Research | Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function [452587] |
| BMC nephrology | Rs10887800 renalase gene polymorphism influences the level of circulating renalase in patients undergoing hemodialysis but not in healthy controls [pubmed:28372594] |
| Nefrología (English Edition) | Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease risk [pubmed:28160962] |
| Clinical?Interventions?in?Aging | Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis [pubmed:27822026] |
| International Journal of?Clinical?and Experimental?Medicine | Aumento de renalasa sérica en pacientes de diálisis peritoneal:? está relacionado con el riesgo de enfermedad cardiovascular? [10.1016:j.nefro.2016.11.013] |
| PLoS One | Relationship between microRNA-146a expression and plasma renalase levels in hemodialyzed patients [pubmed:28614373] |
| Annals of Agricultural and Environmental Medicine | Levels of renalase and advanced oxidation protein products with regard to catecholamines in haemodialysed patients [pubmed:28954489] |
| Angiology | Endocan Concentration in Patients With Primary Hypertension [pubmed:29084442] |
| Journal of Hypertension | RENALASE PLASMA CONCENTRATION BEFORE AND AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION [10.1097/01.hjh.0000523893.07419.ae] |
| International journal of molecular sciences | Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways [pubmed:28448446] |
| Journal of sports medicine and physical fitness | Transient changes in serum renalase concentration during long-distance running: The case of an amateur runner under continuous training [10.7600/jpfsm.6.159] |
| Scientific Reports | Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease?a cross-sectional study [Pubmed:29743680] |
| Life?Sciences | Influence of acute exercise on renalase and its regulatory mechanism [Pubmed:30056018] |
| Experimental?Eye?Research | Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration [Pubmed:29580721] |
| Rapid?Communications?in?Mass?Spectrometry | A new method for quantitative determination of renalase based on mass‐spectrometry determination of a proteotypic peptide labeled with stable isotopes [10.1002:rcm.8167] |
| International?Urology?and?Nephrology | Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats [Pubmed:29476431] |
| Pediatric Cardiology | Serum Renalase Levels in Adolescents with Primary Hypertension [Pubmed:29748702] |
| Postepy?w Kardiologii?Interwencyjnej | Atorvastatin facilitates protection against contrast-induced nephropathy in patients undergoing coronary angiography via humoral mediators rather than?… [Pubmed:30008773] |
| High urinary kidney injury molecule type 1 level is associated with 12-month adverse cardiovascular events in patients with coronary artery disease [publication:324522368] | |
| Journal of?Clinical?Medicine | Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary?… [Pubmed: 30424498] |
| Archives of disease in childhood | GP23 Percutaneous closure of patent ductus arteriosus: single center experience [] |
| Archives of disease in childhood | GP25 Comparison of associations and outcomes of prenatally and postnatally diagnosed right aortic arch: south wales' experience [] |
| Archives of disease in childhood | GP24 Serum renalase levels in adolescents with primary hypertension [] |
| Disease Markers | Association of Plasma Renalase and Left Ventricle Mass Index in Heart Failure Patients Stratified to the Category of the Ejection Fraction: A Pilot Study [Pubmed: 31737132] |
| EXPERIMENTAL BIOLOGY AND MEDICINE | The role of urinary renalase on early-stage renal damage in Chinese adults with primary hypertension [Pubmed: 32102561] |
| FEBS Open Bio | Moderate‐intensity exercise increases renalase levels in the blood and skeletal muscle of rats [Pubmed: 32053739] |
| current medical research and opinion | The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patients [Pubmed: 32297799] |
| Dovepress | Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome [Pubmed: 32982355] |
| 學(xué)位論文 | Nikotinamidadenindinukleotid-Blutplasmawerte sind unabh?ngig vom kalendarischen und vaskul?ren Alter in einer Normalkohorte aus der Region Halle-Saalekreis [] |
| Life | Circulating Renalase as Predictor of Renal and Cardiovascular Outcomes in Pre-Dialysis CKD Patients: A 5-Year Prospective Cohort Study [33800219] |
| Edited by: Background: Renalase has been implicated in chronic heart failure (CHF); however, nothing is known about renalase discriminatory ability and prognostic?… [] |
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